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A UK website, principally for about and carers for schizophrenia; family, community, and professional service caring, who should - must ! - give voice for the best interests of those cared for: they can't, they won't, they don't, voice for themselves

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text me on (44)07547153244

On this page I am going to continue to up date any new items that deal with adult neurogenesis,

because I believe the failure to proliferate enough human hippocampus adult neurogenesis is the proximate cause of schizophrenia.

Lay carers: go on to next page carers of schizophrenia links for carers.

new every month

July 2018 :-
hippocampal neurogenesis in the rat protects from brain oversaturation of longterm memories

helping resilience to stress

"We found that chemogenetic inhibition of adult-born neurons in the vDG promotes susceptibility to social defeat stress, whereas increasing neurogenesis confers resilience to chronic stress."

April 2018 :- 1.

In a letter to the Nature journal meaning - in this case - important news that can't wait for the full article.....

xxx A Bombshell

April 2018 Sorrels et al - there is no human adult neurogenesis in the hippocampus

a previous study agrees

April 2018 :-human adult neurogenesis does exist Boldrini et al

now a comment ... Sorrels Bombshell reviewed
also another review comment

again 'the bombshell' reviewed.

Sorrels - they do say that there are signs of neurogenesis in the lining of brain ventricles, reply to criticism.

But see

Spalding et al ;- radio-active dating of human adult neurogenesis

and Coras as in rodents, human hippocampus has neurogenesis . Its activity correlates with memory ability in the people from whom the sample was surgically taken .

Examining for hippocampus neurogenesis in three sample populations: normal, depression samples showed the the same activity in neurogenesis; schizophrenia had only half that rate of neurogenesis
Reif et al 2006 replicated and verified for continuing schizophrenia - nine years later

by Allen et al

Hippocampal dental gyrus: Neurogenesis proliferation is reduced by over half.

I.e. there is human neurogenesis, shown to be halved in continuing schizophrenia.

adult neurogenesis: humans and dolphins

hippocampus;evolutionary context

Influence of genes carried in the placenta
stress resilience in schizophrenia

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